I have a little home server that I use to store media, email, as a NAS, and as backup storage device. One of the disks was getting quite full, so I decided to add a disk in RAID-0 mode (striped). Luckily this disk was formatted with btrfs, which supports various multiple disk architectures.
Alpine Linux persistent storage on the Raspberry Pi
Alpine runs in memory on the Pi, which is great for performance, security, and for minimizing wear on the SD-card. The downside is that it has no persistent storage. Everything done on such a system is cleared out on reboot.
Alpine Linux
I already said that I like Gentoo Linux, but it can take some effort to keep it up to date, especially on less capable hardware. I tried to install Gentoo on a Raspberry Pi 4B and found a way how to do that, years back. However, that project is dead now, and the successor project on the Gentoo Wiki looks a lot more complicated. I have done those cross compile excercises in the past, and found that it requires even more maintenance than regular Gentoo. No thanks.